Research and Clinical Trials

ALS and Development of Cognitive Change
Brief Description  
This research study is for patients with Amyotrophic Lateral Sclerosis (ALS). The purpose of this research study is to clarify the relationship between ALS and the development of cognitive change. Cognition refers to thinking processes involved in language, memory, spatial skills, and problem solving. Some patients who have ALS may experience subtle changes in their ability to process language and problem-solve. These changes can be detected through testing of thinking, organization, problem-sol
Who may be Eligible  
  • Diagnosis of ALS. All patients recruited will meet revised El Escorial criteria for clinically definite ALS, clinically probable ALS, or clinically probable ALS - laboratory supported 14, as determined by a neurologist.
  • No history of any condition other than ALS that is known to be associated with cognitive changes
  • Age 20 - 85
  • Ability to participate in formal testing through use of spoken, written, or typed communication.
  • Willing and able to provide informed consent.
ALS - Amyotrophic Lateral Sclerosis
IRB Number  
Principal Investigator  
Bravver, Elena

For More Information, Contact  Rachel  M, Skains
Phone:  (704) 446-1910  Fax:  (704) 446-6208  
Address:Carolinas Neuromuscular/ALS-MDA Center Neuroscience and Spine Institute 1010 Edgehill Road North Charlotte, NC 28207-1885