Developmental Therapeutics

When standard cancer therapies aren’t working, Atrium Health Levine Children’s connects kids to clinical trials of the latest, most promising treatments through our developmental therapeutics program. These therapies give hope to families and help researchers gather information that could make future treatments even better.

A comprehensive cancer clinical trials program

Here’s how children benefit from our developmental therapeutics program:

• Access to clinical trials at every phase. Unlike many pediatric hospitals, we have the expertise and resources to offer Phase I clinical trials. This gives some children access to the most innovative therapies before they’re widely available.
• In-house principal investigators (PIs). Many of our doctors design, develop and oversee clinical trials. This means your child can access these trials first, without traveling to a faraway hospital.
• A specialized team. New drugs come with special instructions, and your child’s doctors and nurses need to be aware of potential side effects so they know what to watch for. Our doctors, nurses and research coordinators have special expertise in matching your child with the right trial and in guiding them through treatment. This makes treatment as safe and effective as possible.
• Collaboration with your pediatrician and other providers. This helps us understand your child’s medical history and unique needs, so we can match them with the best possible therapy.
• A large network of research partners. We collaborate with the world’s leading researchers and research organizations. This gives your child access to clinical trials that are available at few other hospitals, including trials for rare cancers.

Improving care through global partnerships

Our physicians work with researchers around the world to offer trials of emerging therapies. Partners include:

• Beat Childhood Cancer, a research consortium that includes over 40 children's hospitals and academic institutions that connect children with new therapies for high-risk pediatric cancers.
• Children's Oncology Group (COG), which brings over 9,000 leading doctors and scientists together to develop new therapies and run clinical trials.
• National Pediatric Cancer Foundation’s Sunshine Project, where top pediatric cancer experts team up to develop treatments and improve survival.
• New Approaches to Neuroblastoma Therapy NANT, a network that connects kids with new treatments for high-risk neuroblastoma.
• Pediatric Brain Tumors Consortium, a nationwide organization where childhood cancer leaders come together to improve pediatric brain tumor care.
• Therapeutic Advances in Childhood Leukemia & Lymphoma (TACL), which connects kids with new medications for pediatric blood cancers.